Immunology
Code
10656
Academic unit
Faculdade de Ciências e Tecnologia
Department
Departamento de Ciências da Vida
Credits
6.0
Teacher in charge
Ana Madalena Peres de Drumond Ludovice Mendes Gomes, Paula Alexandra Quintela Videira
Weekly hours
4
Total hours
80
Teaching language
Português
Objectives
- Acquisition of knowledge about the constitution and function of the Immune System.
- Acquisition of knowledge about the mechanisms of immune response, in the different steps of the immune response.
- Learning of basic principles that relate to cells and molecules of the immune system in the defense against pathogens and how they are developed to recognize antigens.
- Acquisition of knowledge on the role of immune dysfunction in autoimmune diseases and immunodeficiencies.
- Development of skills on the applicability of methodologies / technologies used in the study of Immunology in different areas, such as, basic research and diagnosis.
- Understanding the dynamics of knowledge contained in a rapidly developing science that integrates in all other biomedical sciences.
Prerequisites
Basic knowledge in Cell and Molecular Biology, Molecular Genetics, Microbiology and Biochemistry
Subject matter
|
DATE |
Hour |
TITLE |
TEACHER |
|
08/09 |
12:00 -13:30 |
Introduction / Overview of Immunology |
Paula Videira |
|
15/09 |
12:00 -13:30 |
Innate response |
Paula Videira |
|
22/09 |
12:00 -13:30 |
Immune response mediated by T and B cells |
Paula Videira |
|
29/09 |
12:00 -13:30 |
Antigens and antibodies Cytokines |
Paula Videira |
|
6/10 |
12:00 -13:30 |
Phases of the immune response/ |
Paula Videira |
|
13/10 |
12:00 -13:30 |
Complement system |
Paula Videira |
|
20/10 |
12:00 -13:30 |
Organization and expression of genes of immunoglobulins and T cell receptors Major Histocompatibility Complex |
Paula Videira |
|
27/10 |
12:00 -13:30 |
MINI-TEST |
Paula Videira |
|
3/11 |
12:00 -13:30 |
Tumor Immunology / Immunotherapy |
Paula Videira |
|
10/11 |
12:00 -13:30 |
Immune cells and their identification by flow cytometry Study visit |
Paula Videira |
|
17/11 |
12:00 -13:30 |
Immunohematology |
Paula Videira |
|
24/11 |
12:00 -13:30 |
Vaccines / vaccine production processes |
Paula Videira |
|
1/12 |
12:00 -13:30 |
SEMINARS in Autoimmunity and Hypersensitivities (by students) |
Paula Videira |
|
17/12 |
12:00 -13:30 |
MINI-TEST |
Paula Videira
|
CALENDER OF PRATICAL LECTURES
NOTE: Detailed information on the practical classes, is in a separate document “Monografia das aulas práticas”
|
DATE |
Hour |
TITLE |
TEACHER |
|
08/09 |
14.30 – 17.30 |
Blood cells |
Paula Videira |
|
15/09 |
14.30 – 17.30 |
Cell culture |
Paula Videira |
|
22/09 |
14.30 – 17.30 |
Isolation of leukocytes |
Paula Videira |
|
29/09 |
14.30 – 17.30 |
Leukocyte activation |
Paula Videira |
|
6/10 |
14.30 – 17.30 |
Leukocyte activation by analysis of nitrites |
Paula Videira |
|
13/10 |
14.30 – 17.30 |
ELISA |
Paula Videira |
|
20/10 |
14.00 – 17.30 |
HLA typing |
Paula Videira |
|
27/10 |
14.30 – 17.30 |
Precipitation reactions |
Paula Videira |
|
3/11 |
14.30 – 17.30 |
Students presentation |
Paula Videira |
|
10/11 |
14.30 – 17.30 |
Study visit Flow cytometry and phagocytosis |
Paula Videira
|
|
17/11 |
14.30 – 17.30 |
Immunohematology |
Paula Videira |
|
24/11 |
14.30 – 17.30 |
Immunization and Antibody technology |
Paula Videira |
|
1/12 |
14.30 – 17.30 |
SEMINARS students |
Carlos Novo Paula Videira |
Bibliography
Fundamentos de Imunologia, Lidel - Edições Técnicas, 2ª edição por Fernando A. Arosa, Elsa M. Cardoso e Francisco C. Pacheco
Cellular and Molecular Immunology, Saunders/Elsevier, 2011 by Abbas, Lichtman, and Pillai
Janeway’s Immunobiology; Garland Science, by Murphy, Travers, Walport
Kuby Immunology; Kindt, Goldsby, Osborne
Scientific articles e.g. , Nature Immunology, Nature Reviews Immunology, Journal of Immunology, Molecular Immunology, European Journal of Immunology and others.
Teaching method
Teaching is mainly based in theoretical and practical lectures allowing students to acquire and apply knowledge in the field of Immunology. It is intended to attract students from the beginning to the study of immunology, foster discussion and criticism, cementing the knowledge, enable inter-relate the various issues and even with other areas of biological sciences and create foundations for the eventual implementation of Immunology their future work.
Evaluation method
The assessment of this unit is continuous. The assessment components are:
(A) theoretical and practical assessment;
i) Consisting of two assessment elements: two mini-tests. Each mini-test has a weight of 22.5% each (total value of mini-tests = 45%) and include theoretical, practical matters and each has a maximum duration of 60 minutes.
(B) laboratory or project assessment;
i) - Group work: weight of 20%. The themes, content and organization will be defined in the first two weeks of classes. The classification of work entails the development of a mini thesis and presentation in the form of seminar and discussion.
ii) - individual or small group work: weight of 15%. The themes, content and organization will be set up mid-semester classes. The classification of work involves drafting a protocol in English.
(C) summative assessment;
i) - Resolution of small questionnaires after the practice sessions: recovery of 15%
ii) - Participation and attendance in class: 5% appreciation of
Rating
Ai*45% + Bi*20% + Bii*15% + Ci*15% + Cii*5%
40% of the evaluation will be held until the eighth week of the semester.
The minimum required for each component rating is 5/20.
All enrolled students must attend at least 2/3 of practical classes.
In the case of grade improvement in exam, the grades of elements such as group work, individual work and participation during the class may remain.
In case of repetition of the discipline, the frequency of theoretical and practices lectures is valid for two years. During these two years, the student can choose to keep the score obtained prior to any of the assessment components, provided that the grades for that component has been higher than 10. However, the student must always validate the grade given through a small practical test (to match the conductor), to ensure their notes.