Clinical Biochemistry
Code
10783
Academic unit
Faculdade de Ciências e Tecnologia
Department
Departamento de Química
Credits
6.0
Teacher in charge
Carlos Alberto Gomes Salgueiro, José Ricardo Ramos Franco Tavares
Weekly hours
5
Total hours
92
Teaching language
Português
Objectives
- To acquire knowledge and skills in Clinical Biochemistry.
- To be familiar with the basic aspects of quality control in this area.
- To understand the metabolic processes and associated pathologies.
- To know the experimental methods used to quantitatively and/or qualitatively determine the molecules associated with metabolic disorders.
- To be able to interpret biochemical analysis and know the appropriate therapies.
- To be able to search and interpret critically the literature.
Subject matter
1. Introduction to Clinical Biochemistry
2. Basic notions of quality control in the Clinical Biochemistry Laboratory
3. Methods in Clinical Biochemistry.
4. Conditions associated with impaired hidroelectrolytic and acid-base balance.
5. Renal function and urinalysis. Analysis of clinical histories.
6. Hepatic function and related conditions.
7. Conditions associated with carbohydrate, lipid and protein metabolism.
8. Pancreatic and gastric functions and asociated conditions.
9. Muscle metabolism.
10. Endocrinology
11. Biochemical markers: myocardial infarction; hepatic function; tumor markers.
Bibliography
- Donald Voet, Judith G. Voet. Biochemistry. 3rd Edition, John Wiley & Sons, 2004.
- Donald Voet, Judith G. Voet, C. W. Pratt. Fundamentals of Biochemistry. 3rd Edition, John Wiley & Sons, 2008.
- Thomas Devlin. Textbook of Biochemistry with Clinical Correlations. 6th Edition, Wiley-Liss, 2006.
- Allan Gaw, Michael J. Murphy, Robert A. Cowan, Denis St. J. O''''''''''''''''''''''''''''''''Reilly, Michael J. Stewart, James Shepherd. Clinical Biochemistry: An Illustrated Colour Text. 4th Edition, Churchill Livingstone Elsevier, 2008.
- R. Swaminathan. Handbook of Clinical Biochemistry. Oxford University Press. 2004
Teaching method
The course includes lectures and problem-solving classes. The lectures will be taught using "data show", accompanied by supplementary bibliography previously available on the website of discipline. In the presentation, a diagnostic test will be distributed, which will focus on subjects considered essential for the student to grasp the concepts presented in this course.
The problem-solving and laboratorial classes will focus on discussion of clinical cases, for which students will present a seminar focusing on the experimental strategies best suited to its analysis and resolution, from the laboratorial point of view. Clinical cases will be drawn into debate among students, organized into groups.