Translational Research
Code
101030
Academic unit
NOVA Medical School | Faculdade de Ciências Médicas
Credits
5
Teacher in charge
Profª. Doutora Maria Paula Borges de Lemos Macedo
Teaching language
English
Objectives
Translational Medicine is defined as scientific research that helps speed up the translation of scientific discovery into clinical practice and effective amelioration of human health and wellbeing. Thus, Translational Medicine is responsible for bridging the gap, exploring and converting, from basic research or population studies into clinical application, potentiating the available instruments of diagnosis, monitoring, and treatment of specific pathologies. By the end of the course students must have acquired knowledge and competences regarding the entire process associated with Translational Medicine.
Prerequisites
n/a
Subject matter
-Basic Discovery: the Foundation of Translational Medicine
-From the Clinic to the Bench and back to Clinic
-Designing translational medicine projects:
-Academic/Industrial Partnerships in Drug Development
-Modern Biomarker Discovery: Omics approaches
-Regenerative medicine
-Tales of Translational Medicine (Study Cases) and grant proposal in translational medicine
Bibliography
Principles of Translational Science in Medicine. From Bench to Bedside. Edited by: Martin Wehling, Ruprecht-Karls-Universität Heidelberg, Germany, 2010.
Translational Medicine: The Future of Therapy? Edited by: James Mittra; Christopher-Paul Milne by Pan Stanford Publishing, 2013.
Translational Medicine: Strategies and Statistics Methods. Dennis Comatos and Shein-Chung Chow (eds) 1st edition, CRC Press, 2008
EATRIS, a European initiative to boost translational biomedical research; Guus AMS van Dongen, Anton E Ussi3, Frank H de Man, Giovanni Migliaccio; Am J Nucl Med Mol Imaging 2013;3(2):166-174.
"What great creation". FitzGerald GA. Sci Transl Med. 2012 Oct 3;4(154).
Other original articles from recent findings based on translational medicine.
Teaching method
This course is based on swift theoretical introductions, designed to give context regarding the fields of knowledge to be explored, meant to be further detailed by the students themselves through the preparation and discussion. These debates are to be complemented by the students critical analysis of scientific papers in Translational Medicine.
Multidisciplinar and translational learning is to be paired with an effective mentoring approach, in wich the students will be divided in 3-4 working groups, with a tutor/group, accompanied by faculty/researcher members with availability and ability to share knowledge and offer guidance. This will facilitate the development of the trainee into becoming an independent investigator.
Evaluation method
Evaluation will include a final project in translational medicine evaluation (50%), class participation and the ability to argue (15%), to present and discuss scientific papers (15%), success in applying acquired knowledge to translational research (20%).
Courses
