Rational Prescription of Medicines
Code
11210
Academic unit
NOVA Medical School|Faculdade de Ciências Médicas
Department
MC
Credits
3
Teacher in charge
Prof. Doutor José Delgado Alves
Teaching language
Portuguese
Objectives
|
The general learning objectives of the Rational Prescription of Medicines unit are: 1. Understanding the processes involved in developing a medicine, with emphasis on the clinical phase. 2. Identifying the global security mechanisms in place for controlling for side effects. 3. Understanding the importance of economic factors in decision-making related to making new medicines available in the context of national health systems. |
Prerequisites
Subject matter
|
Pharmacovigilance; Pharmacogenetics and personalised medicine. Introduction to pharmacoeconomics. . Pharmacoepidemiology and the rational prescription of medicines. Clinical epidemiology concepts in therapeutics. Assessment of pharmacological therapeutics from an Evidence Based Medicine (EBM) Writing guidelines/Clinical Practice Guidelines. Types of therapeutics. Pharmacological and non-pharmacological therapeutics Introduction to the rational prescription of medicines.Prescription. Information. Monitoring. Ethical issues associated with the (rational) prescription of medicines. Determining factors in the prescription of medicines. Formulary practical aspects. Selection of pharmaceuticals for the treatment of common conditions: arterial hypertension, cardiac insufficiency. Selection of pharmaceuticals for the treatment of less common conditions: rheumatoid arthritis, multiple myeloma. |
Bibliography
|
Clinical Epidemiology. A Basic Science for Clinical Medicine. Second Edition. Little, Brown and Company; 1991. Clinical Epidemiology. The Essentials. Third edition. Lippincott Williams & Wilkins; 1996. Piantadosi S. Clinical Trials. A Methodological Perspective. Second Edition. Wiley - Interscience; 2005. Farmacovigilância em Portugal. INFARMED - Instituto Nacional da Farmácia e do Medicamento. Ministério da Saúde. 2003. Goodman and Gilmans The Pharmacological Basis of Therapeutics, Twelfth Edition. 2011. Textbook of Pharmacoepidemiology. 3aedition, eletronic edition. John Wiley & Sons, LTD; 2006. World Health Organization. The Pursuit of Responsible Use of Medicines: Sharing and Learning from Country Experiences. 2012. Orientações metodológicas para Estudos de Avaliação Económica de Medicamentos. INFARMED Instituto Nacional da Farmácia e do Medicamento; 1999. |
Teaching method
The Curricular Unit on the Rational Prescription of Medicines is semester long course. It is worth 3 ECTS credits, which corresponds to 2 hours of mixed theoretical/practical classes per week. Classes take place weekly and each class is 1hr 50 min long. In order to optimise learning, student will be divided into 4 groups, each with classes at different times and in different rooms. Depending on the subject under discussion, some classes might be given as seminars or with the entire class of students together at the same time.
Evaluation method
A avaliação será realizada com base em prova escrita, constituída por 40 perguntas de resposta de escolha múltipla com 5 alternativas, podendo existir 1 a 4 opções corretas. Opções erradas serão contabilizadas de forma negativa, apenas na respetiva pergunta, não sendo uma eventual pontuação negativa de uma pergunta transportada para as respostas seguintes.
Assessment will be carried out through a final written exam consisting of 40 multiple choice questions, each with 5 possible answers, of which between 1 and 4 may be correct. Incorrect answers will be penalised, but only within the score for that particular question i.e. an incorrect answer will not impact the score for subsequent questions.
A pass grade is 9.5 out of 20 or above