Membrane Contactors and Bioreactors
Code
10190
Academic unit
Faculdade de Ciências e Tecnologia
Department
Departamento de Química
Credits
6.0
Teacher in charge
Isabel Maria Rola Coelhoso
Weekly hours
6
Total hours
57
Teaching language
Português
Objectives
- To acquire general concepts about Membrane Contactors and Bioreactors
- To be able to design Membrane Bioreactors and Membrane Contactors
- To be able to design process integration schemes
- To acquire knowledge about emerging process monitoring tools and their use for process control
- Understand how a specific problem may be approached by the Industry
Subject matter
Bioreactors:
Fundamentals on Cell growth and metabolism
Production of bioproducts
Synthesis of biological macromolecules
Substrate transport mechanisms
Primary metabolism
Cell growth kinetics – batch growth
Maintenance metabolism
Kinetics of product formation
Elemental composition of biomass (stoichiometry and elemental balances)
Reaction rates and yield coefficients
Kinetics for a steady-state CSTR
Enzymatic Bioreactors
Cell Membrane bioreactors
Pressure driven Cell Membrane bioreactors
Configuration of reactors, membranes and different biology; Operating parameters
Fouling formation, anti-fouling strategies and monitoring techniques
MBR applications: case studies
Membrane contactors: fundamentals and applications. Stability, operation mode and membrane selection.
Membrane contactors: equipment design. Mass transfer correlations.
Unit operations in membrane contactors: Liquid –liquid extraction and Gas-liquid absorption; OD and MD; Crystallization and Emulsification
Hybrid Processes
Monitoring and Modelling
Modelling as a monitoring tool
Metabolic modelling
Non-parametric Modelling
Bibliography
Bailey JE, Ollis DF. Biochemical Engineering Fundamentals. 2nd ed. McGraw-Hill, New York, 1986.
Nielsen J, Villadsen J, Lidén G. Bioreaction Engineering Principles. 2nd ed. Kluver Academic/Plenum Publishers, New York, 2003.
Judd S. The MBR Book: Principles and Applications of Membrane Bioreactors in Water and Wastewater Treatment. Elsevier, Amsterdam, 2006.
A. Gabelman, S. Hwang, Hollow fiber membrane contactors Journal of Membrane Science 159 (1999) 61-106.
Evaluation method
The evaluation includes:
- Laboratory sessions (2) and corresponding reports and discussion – group of 3 students.
- Proposal of a scientific project and oral presentation and discussion - individual.
- Tests (2) - individual
The final grade is composed by 25% of the grade obtained in the lab sessions (average value of the two experimental works) +25% of the grade obtained in the proposal +50% of the grade obtained in the tests (average value of the two tests).
In each component of the evaluation the grade has to be >=9.5, in a scale 0-20.