Faculdade de Ciências e Tecnologia

Membranes in Downstream Processing

Code

10191

Academic unit

Faculdade de Ciências e Tecnologia

Department

Departamento de Química

Credits

6.0

Teacher in charge

Isabel Maria Rola Coelhoso, João Paulo Serejo Goulão Crespo

Weekly hours

4

Total hours

57

Teaching language

Inglês

Objectives

  1. To acquire general concepts about downstream processing
  2. To be able to apply previous knowledge, acquired in separation processes and transport phenomena, in the processing of biological media
  3. To be able to design process integration schemes
  4. To acquire knowledge about emerging process monitoring tools and their use for process control
  5. Understand how a specific problem may be approached by the Industry

Subject matter

  1. Introduction and general concepts
  2. Specificity of biological complex media and media /membrane interactions
  3. Product recovery and fractionation
  4. Product purification and polishing
  5. Hybrid processes and process integration
  6. Process monitoring and control

Bibliography

-        Monitoring and visualizing membrane based processes. Edited by Carme Güell, Montserrat Ferrando, Francisco López. 2009 Wiley-VCH Verlag GmbH & Co. KGaA Weinheim;

-        Microfiltration and Ultrafiltration: Principles and applications. Leos J. Zeman and Andrew L. Zydney, 1996 Marcel Dekker, Inc., New York;

-        A. Fersht, Structure and Mechanism in Protein Science,W.H. Freeman and Company, New York, 1999.

-        B. Valeur, Molecular Fluorescence. Principles and Applications, Wiley/ VCH, Germany, 2002.   

-        Marcel Mulder, Basic Principles of Membrane Technology, Kluwer Academic Press, 1996.

-        E.L. Cussler, Diffusion, second ed., Cambridge University Press, Cambridge, 1997;

Evaluation method

The evaluation includes:

  1. Laboratory sessions (2) and corresponding reports and discussion – group of 3 students.
  2. Proposal of a scientific project and oral presentation and discussion - individual.
  3. Tests (2) - individual

The final grade is composed by 25% of the grade obtained in the lab sessions (average value of the two experimental works) +25% of the grade obtained in the proposal +50% of the grade obtained in the tests (average value of the two tests).

In each component of the evaluation the grade has to be >=9.5, in a scale 0-20. 

Courses