Bioinorganic Chemistry
Code
10694
Academic unit
Faculdade de Ciências e Tecnologia
Department
Departamento de Química
Credits
6.0
Teacher in charge
Carlos Lodeiro Espino
Weekly hours
4
Total hours
64
Teaching language
Português
Subject matter
- Introduction to Bioinorganic Chemistry
- Chemical Reactions stoichiometry
- Nomenclature and isomerism in coordination complexes
- Chemical bonding in coordination compounds (HSAB theory)
- Reactivity in coordination compound; Substitution reaction; Inert and labile compounds; Reactions mechanisms
- Complexation equilibria; parcial and global stability constants; effect of pH and presence of other ligands
- Magnetism and color in coordination compounds; Cristal field Theory
- Oxidation-reduction reactions: Galvanic cell; Balance of redox equilibria; Nernst equation; effect of pH and complex formation; Latimer and Frost diagrams and its application to biological systems
- Metal centers of proteins and enzymes; role of metal ions in biological systems.
Bibliography
Robert Crichton “Biological Inorganic Chemistry: An Introduction”, 2007, 1ª edição, Elsevier Science
Ana M. V. Cavaleiro “Química Inorgânica Básica”, 2004, 3ª edição, Universidade de Aveiro
Raymond Chang and Kenneth A. Goldsby, “Chemistry”, 2012, McGraw-Hill, N.Y., 11ª edição
Patricia C. Wilkins, Ralph G. Wilkins “Inorganic Chemistry in Biology”, Oxford Chemistry Primers, 2002, 2ª edição, Oxford University Press
J. J. R. Fraústo da Silva, R. J. P. Williams “The biological chemistry of the elements: the inorganic chemistry of life”, 2001, 2ª edição, Oxford University Press
José J. G. Moura, Nuno Palma “Introdução à química da vida: caderno de adequação ao ensino à distância”, 1995, 1ª edição, Universidade Aberta