Bionanotechnology
Code
9192
Academic unit
Faculdade de Ciências e Tecnologia
Department
Departamento de Ciências da Vida
Credits
6.0
Teacher in charge
José Ricardo Ramos Franco Tavares, Pedro Miguel Ribeiro Viana Baptista
Weekly hours
5
Total hours
62
Teaching language
Português
Objectives
The main purpose of this course is to raise awareness towards the increasing relevance of nanotechnology, with particular emphasis on nanotechnology in biomedical applications.
In particular, it is intended to stimulate the students’ understanding of concepts and underlying mechanisms of nanotechnology applications in biodiagnostics and construction of biosensors, within a broader field of developments in clinical diagnostics and biomedicine research.
Subject matter
Historic perspective on the origin of Nanotechnology
Scale effect and properties of nanomaterials.
Nanofabrication: bottom-up vs. top-down approach
Microscopy for nanomaterials characterisation (TEM, SEM, SPR)
Bionanotechnology and Bionanomachines
Nanoparticles for clinical applications
Nanotechnology and Green Chemistry
Nanotoxicology
Construction of nanostructures
Surface functionalisation
Self-assembling
Bio-polymerisation
Cross-linking
DNA based nanostructures
Electronics
Bio-mimetizing
Protein based nanostructures
Bionanodetection applications
DNA & RNA (cross-linking vs. non-cross-linking)
Nanoparticles for drug delivery and nanovectors for gene therapy.
Bibliography
“Nanobiotechnology: Concepts, Applications and Perspectives”
C.M. Niemeyer, C.A. Mirkin (Eds.), 2004, Wiley-VCH, Weinhein, Germany
“Materials Chemistry”
B.D. Fahlman, 2007, Springer, Dordrecht, the Netherlands
“Bionanotechnology”, D.S. Goodsell, 2004, Wiley-Liss, Hoboken, NJ, USA
Teaching method
Theoretical classes of exposition with 2 h duration, includign problem solving. Practical laboratory classes with 3 h duration that include the laboratory implementation and accomplishment of protocols and a written report.
Evaluation method
This class has a "Seminar" typology, with no final Exam and no possibilty of grade improvement.
Parameters contribution to the final grade:
1) Monograph in group of selecetd themes (40%)
2) “Peer review” of the monograph from a different group (15%)
3) Reports on the practical sessions (P1 to P4) oral presentation and discussion (25%)
4) Individual evaluation: abstract writing on appaer from which the abstract has been deleted (10%)
5) “Pitch” and oral discussion in class of selected themes (10%)