Immunology
Code
10656
Academic unit
Faculdade de Ciências e Tecnologia
Department
Departamento de Ciências da Vida
Credits
6.0
Teacher in charge
Ana Madalena Peres de Drumond Ludovice Mendes Gomes, Paula Alexandra Quintela Videira
Weekly hours
4
Total hours
81
Teaching language
Português
Objectives
- Acquisition of knowledge about the constitution and function of the Immune System and the mechanisms of immune response, in the different steps of the immune response.
- Learning of basic principles that relate to cells and molecules of the immune system in the defense against pathogens and how they are developed to recognize antigens.
- Acquisition of knowledge on the role of immune dysfunction in autoimmune diseases and immunodeficiencies.
- Development of skills on the applicability of methodologies / technologies used in the study of Immunology in different areas, such as, basic research and diagnosis.
- Understanding the dynamics of knowledge contained in a rapidly developing science that integrates in all other biomedical sciences.
Prerequisites
Basic knowledge in Cell and Molecular Biology, Molecular Genetics, Microbiology and Biochemistry
Subject matter
CALENDAR OF THEORETICAL CLASSES
|
DATE |
TITLE |
|
11/09 |
Introduction / Overview of Immunology |
|
18/09 |
Innate response |
|
25/09 |
Immune response mediated by T and B cells |
|
2/10 |
Antigens and antibodies |
|
9/10 |
Phases of the immune response/ |
|
16/10 |
Complement system |
|
23/10 |
Major Histocompatibility Complex |
|
30/10 |
Organization and expression of genes of immunoglobulins and T cell receptors
|
|
25/10 |
MINI-TEST |
|
6/11 |
Cytokines and Immunotherapy I |
|
13/11 |
Tumor Immunology / Immunotherapy II |
|
20/11 |
Immunohematology |
|
27/11 |
Hypersensitivities |
|
11/12 |
Vaccines / vaccine production processes |
|
|
|
|
|
|
|
16/12 |
MINI-TEST |
|
|
|
|
|
|
CALENDER OF PRATICAL LECTURES
NOTE: Detailed information on the practical classes, is in a separate document “Monografia das aulas práticas”
|
WEEK |
TITLE |
|
11/09 |
Blood cells |
|
18/09 |
Cell culture |
|
25/09 |
Isolation of leukocytes & Leukocyte activation |
|
2/10 |
STUDY |
|
9/10 |
Leukocyte activation by analysis of nitrites |
|
16/10 |
ELISA |
|
23/10 |
Preparation of a protocol |
|
30/10 |
Students presentation |
|
4/11 |
Precipitation reactions |
|
6/11 |
Flow cytometry and phagocytosis |
|
13/11 |
Antibody production |
|
20/11 |
STUDY |
|
|
|
|
|
|
|
|
|
|
|
|
|
(30/11 4/ 12) |
SEMINARS students |
|
7/12 (15/ 12) |
SEMINARS students |
Bibliography
- Janeway’s Immunobiology; nineth edition, Garland Science, by Kenneth Murphy and Casey Weaver
- Fundamentos de Imunologia, Lidel - Edições Técnicas, 2ª ediçao, por Fernando A. Arosa, Elsa M. Cardoso e Francisco C. Pacheco
- Cellular and Molecular Immunology, Saunders/Elsevier, 2011 by Abbas, Lichtman, and Pillai
- Kuby Immunology; Kindt, Goldsby, Osborne
Teaching method
Teaching is mainly based in theoretical and practical lectures allowing students to acquire and apply knowledge in the field of Immunology. It is intended to attract students from the beginning to the study of immunology, foster discussion and criticism, cementing the knowledge, enable inter-relate the various issues and even with other areas of biological sciences and create foundations for the eventual implementation of Immunology their future work.
Evaluation method
The assessment of this unit is continuous. The assessment components are:
(A) theoretical assessment;
i) Consisting of mini-tests. Each mini-test has a weight of 25% each (total value of mini-tests = 50%) and include theoretical matters and each has a maximum duration of 60 minutes.
(B) laboratory or project assessment;
i) – Seminar /group work: weight of 25%. The themes, content and organization will be defined in the first two weeks of classes. The classification of work entails a presentation in the form of seminar and discussion.
ii) - Report: weight of 15%. Report and discussion of experiments.
iii) - Resolution of questions during the practical lectures: weight of 5%
(C) summative assessment;
ii) - Participation and attendance in class:
Classification attributed to final grade:
A Good - rises 1 point to note
B Enough -gets 0 points to note
C Bad- decreases 1 value
Rating
Ai*50% + Bi*25% + Bii*20% + Biii*5%
Only the final grade is rounded !
40% of the evaluation will be held until the eighth week of the semester.
The minimum required for each component rating is 8/20.
All enrolled students must attend at least 2/3 of practical classes.
In the case of grade improvement in exam, the grades of elements such as group work, individual work and participation during the class may remain.
In case of repetition of the discipline, the frequency of theoretical and practices lectures is valid for two years. During these two years, the student can choose to keep the score obtained prior to any of the assessment components, provided that the grades for that component were higher than 10. However, the student must always validate the grade given through a small practical test (to match the conductor), to ensure their notes.