NOVA Medical School | Faculdade de Ciências Médicas

Biomedicine: Historical Perspective

Code

11113

Academic unit

NOVA Medical School | Faculdade de Ciências Médicas

Department

TRA - Population Health

Credits

3

Teacher in charge

Prof. Doutora Isabel Amaral

Teaching language

Portuguese

Objectives

      Course main objectives

This course will be about the discovery and understanding of biomedicine, exploring its uniqueness in the history of science and medicine. Students will gain familiarity with historiographic developments which provide them with a broad outline of the historical context. This way, students become conscious of what is Science and of what is History.

Specific objectives: This course is intended: 1. To understand the concept of biomedicine, from the perspective of the laboratory as an obligatory passageway. 2. To apply the notion of biomedicine to the emergence of molecularization and molecular disease in XX century.

 

Prerequisites

 

Subject matter

Syllabus

This UC takes place over 14 weeks, one topic each week.

Besides topics, contents include concepts: molecularization, tacit knowledge, geography of scientific knowledge (intellectual and political migrations), centre of calculation network, prematurity, Big Science.

 

Topics

1. Introduction. What is biomedicine vs medicine?

2. Vitamins and the dynamics of molecularization

3. Molecular therapeutics from human blood: Edwin Cohn’s Wartime enterprise

4. Corino de Andrade’s disease

5. Lipoprotein’s trajectory: between the laboratory and the clinic

6. History of the early oral contraceptive pill clinical trials, 1950-1959

7. The social construction of coronary heart disease risk factors: Framingham Heart Study

8. Genre and Science in ‘The double helice’

9. Fighting infection: Tuberculosis

10. Insulin: from discovery to therapeutics

11. Histories of penicillin

12. Cancer from research perspective vs from a clinician perspective

13. Pharmaceutical industry and medical research in XX century

14. Brief presentation of final papers by the students

Bibliography

     Bibliography

Collingwood, R. G., The idea of history, (Martino Fire Books, 2014)

IV and V parts.

 

Kragh, Helge, An introduction to the historiography of science, (Cambridge, Cambridge University Press, 1987)

 

Löwy, Ilana, Historiography of biomedicine: ‘Bio’, ‘Medicine’ and In Between, Isis, 102:1, 116-122, http://www.jstor.org/stable/10.1086/658661

 

Kuhn, Thomas S., The structure of scientific revolutions: 50th anniversary edition (London, The University of Chicago Press, 2012)

 

Canguilhem, Georges, The Normal and the pathologic (New York, Zonebooks, 2007)

 

Bachelard, Gaston, The new scientific spirit, (Beacon Press, 1986)

 

Foucault, Michel, Naissace de la clinique, (Paris, Quadrige, 2003)

 

Cambridge illustrated history of medicine, Ed. Roy Porter, (Cambridge, Cambridge University Press, 2006)

 

Alberto Cambrosio et Peter Keating, ‘Qu’est-ce que la biomédecine? repères sócio-historiques’, M/S:médecine sciences, 19:12, 2003, 1280-1287, http://id.erudit.org/iderudit/007405ar

 

Science in the Twentieh Century, ed. J. Kridge & D. Pestre, (Amsterdam, Harwood Academic Publishers, 1997)

Teaching method

2h theoretical-practical classes every week.

We will use original research papers, historical accounts as well as reference articles regarding the concepts referred on Syllabus. Forty to fifty minutes of theoretical exposition on one of the referred concepts followed by the presentation of students assignments. For this purpose students will be grouped in three elements, being mandatory each student intervene in the presentation.

 

Evaluation method

Assessment: it will be distributed throughout the semester without final examination. Oral presentation and participation on topic discussion: 50%. Each student has to write a research essay pursuing a topic either from class themes or from his/her interest (within the history of biomedicine) of about 15 pp., corresponding to 50% of the final mark. This paper will be discussed orally on the date indicated for examination of the optional disciplines.

Assessment:

It is done throughout the semester, without final exam.
The essays will be individual and discussed in person on the dates indicated for the examinations of the optional disciplines.

Attendance: 2/3 attendance is required and it is not possible to offer substitution classes. It is important that the student does not miss the class where he/she is due with his/her presentation.

 

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