Molecular Bases of Disease
Code
11179
Academic unit
Faculdade de Ciências e Tecnologia
Department
Departamento de Ciências da Vida
Credits
6.0
Teacher in charge
Ligia Raquel Mendonça Faria Marques Saraiva Teixeira, Paula Alexandra Quintela Videira
Weekly hours
5
Total hours
70
Teaching language
Português
Objectives
At the end of this course, the students should have acquired knowledge, skills and competences enabling him to:
- To acquire knowledge and skills about the biochemical mechanisms underlying human disease.
- To understand metabolic processes and associated pathologies.
- To be able to relate biochemical mechanisms with associated pathologies
- To acquire knowledge about specific diseases, on a seminar context, and to be able to develop critical analysis, using the scientific literature.
- To be able to search and critically interpret the literature.
Prerequisites
Basic knowledge in Cell and Molecular Biology, Molecular Genetics, Microbiology and Biochemistry.
Subject matter
- Molecular aspects underlying several diseases. t includes injury and cellular homeostasis, genetic deficits, changes in metabolism, inflammation and infection, cancer and aging. Seminars on various diseases: metabolic, immune, cardiovascular, infectious, rare diseases, cancer and aging.
- Current therapies and methodologies in the context of understanding of human diseases.
Lectures can be given in Portuguese or English.
Bibliography
- Robbins Basic Pathology, 10th Edition, 2018, by Vinay Kumar, MBBS, MD, FRCPath, Abul K. Abbas, MBBS and Jon Aster, MD. ISBN: 9780323353175
-Essential Concepts in Molecular Pathology. (2010) William B. Coleman and Gregory J. Tsongalis (Eds), Academic Press.
-Molecular Basis of Health and Disease (2011) Undurti N. Das, Springer.
Teaching method
The course includes theoretical, theoretical-practical classes and seminars. The lectures will be taught using the "data show", accompanied by complementary bibliography previously available on the website of discipline.
The theoretical-practical classes and seminars will focus on discussion of specialized subjects. The seminars include lectures by invited speakers followed by discussions with active student participation. Also includes student’s seminars.
Evaluation method
The final test on theoretical class themes - (minimum 10 values) - 70%
Case resolution -5%
Quizzes- 10% (0-20)
Seminars (seminar summary)- 15%
Classification attributed to seminars: I (0), S (10), B(15), B+ (18), MB (20)
The final grade results from the weighting of the grade of all seminars.
Delays of more than 20 minutes after the start of the seminar class will be counted as an absence.
Absences at seminars imply a zero mark.
More than 3 absences to seminars - the practical part is considered to be not done.
The final mark (seminars+ case or theoretical part) is kept for 2 years.