Molecular Biomedicine
Code
11853
Academic unit
Faculdade de Ciências e Tecnologia
Department
Departamento de Ciências da Vida
Credits
3.0
Teacher in charge
Maria Alexandra Núncio de Carvalho Ramos Fernandes, Pedro Miguel Ribeiro Viana Baptista
Weekly hours
2
Total hours
26
Teaching language
Português
Objectives
The main objective is to provide students with an overview of the use of molecular technologies in medicine and the relevance of Biomedicine in research.
Specifically, to investigate application of molecular structures in biomedicine: diagnostics and therapeutics; biomedical applications; smart design; nanotechnology for biomedicine.
Subject matter
- Molecular mechanisms in cell control
- Molecular actuators
- Smart design of molecular structures
- Biosensing applications
- Molecular therapeutics
- Therapeutic nucleic acids: gene silencing and dose compensation
- in vitro models
- in vivo models
- Drug discovery, development and validation
- Bionanotechnology and Bionanomachines
- Regenerative systems
- Translation, ethical and societal impact, regulation.
Bibliography
New Advances on Disease Biomarkers and Molecular Targets in Biomedicine; 2013; ISBN-13: 978-1627034555 ISBN-10: 1627034552
Biomedicine; 2012; ISBN 978-953-51-0352-3
Systems Biomedicine: Concepts and Perspetives; 2009; ISBN: 978-0-12-372550-9
Complex Systems Science in Biomedicine; 2006; ISBN: 978-0-387-30241-6; 978-0-387-33532-2
Teaching method
Seminar.
Lectures for itroductory themes; Theme discussion in - working in group. Team work to prepare assay on speciic theme that is then presneted and discussed open in forum.
Evaluation method
Evaluation: Monograph on a theme (25%) ; oral presentation and discussion of monograph (55%). Mini-quiz (10%). Scientific paper discussion (10%);