Bionanotechnology
Code
9192
Academic unit
Faculdade de Ciências e Tecnologia
Department
Departamento de Química
Credits
6.0
Teacher in charge
José Ricardo Ramos Franco Tavares, Pedro Miguel Ribeiro Viana Baptista
Weekly hours
7
Total hours
55
Teaching language
Português
Objectives
The main purpose of this course is to raise awareness towards the increasing relevance of nanotechnology, with particular emphasis on nanotechnology in biomedical applications.
In particular, it is intended to stimulate the students’ understanding of concepts and underlying mechanisms of nanotechnology applications in biodiagnostics and construction of biosensors, within a broader field of developments in clinical diagnostics and biomedicine research.
Subject matter
Historic perspective on the origin of Nanotechnology
Scale effect and properties of nanomaterials.
Nanofabrication: bottom-up vs. top-down approach
Microscopy for nanomaterials characterisation (TEM, SEM, SPR)
Bionanotechnology and Bionanomachines
Nanoparticles for clinical applications
Nanotechnology and Green Chemistry
Nanotoxicology
Construction of nanostructures
Surface functionalisation
Self-assembling
Bio-polymerisation
Cross-linking
DNA based nanostructures
Electronics
Bio-mimetizing
Protein based nanostructures
Bionanodetection applications
DNA & RNA (cross-linking vs. non-cross-linking)
Nanoparticles for drug delivery and nanovectors for gene therapy.
Bibliography
“Nanobiotechnology: Concepts, Applications and Perspectives”
C.M. Niemeyer, C.A. Mirkin (Eds.), 2004, Wiley-VCH, Weinhein, Germany
“Materials Chemistry”
B.D. Fahlman, 2007, Springer, Dordrecht, the Netherlands
“Bionanotechnology”, D.S. Goodsell, 2004, Wiley-Liss, Hoboken, NJ, USA
Teaching method
Theoretical classes of theoretical exposition, including problem solving. Seminars by invited Specialists. Seminars on several established and emerging topics in Bionanotechnology, given by the students in Groups of 3. Time for ample classroom discussion in reserved after the Seminars.